Currently, I'm a postdoc in Steve Henikoff's lab at the Fred Hutchinson Cancer Research Center. I'm generally interested in the evolutionary role of losses in gene function. My training and experience is primarily in population genetics (especially balancing selection) and genome analysis. More on my project in the Henikoff lab as it evolves.
Education:
Ph.D., Genetics, 2006
“The Role of Balancing Selection in Maintenance of Natural Genetic Variation” pdf
Advisor: Dr. Maynard Olson
B.S., Biology – Genetics and Development, 1995
Work Experience:
University of Washington Genome Center (1995-1999)
Publications:
Detecting Disease-Causing Mutations in the Human Genome by Haplotype Matching. David H. Spencer, Kerry L. Bubb, and Maynard V. Olson. Am. J. Hum. Genet. 2006 Nov;79(5):958-64. pdf
Scan of human genome reveals no new Loci under ancient balancing selection. K. L. Bubb,
Analysis of xbx genes in C. elegans. Evgeni Efimenko,
Hypervariability, suppressed recombination and the genetics of individuality. M. V. Olson, A. Kas, K. Bubb, R. Qui, E. E. Smith, C. K. Raymond, R. Kaul. Philos Trans R Soc Lond B Biol Sci. 2004 Jan 29;359(1441):129-40. PMID: 15065665 pdf
Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Joshua McElwee, Kerry Bubb and James H. Thomas. Aging Cell. 2003 Apr;2(2):111-21. Erratum in: Aging Cell. 2003 Dec;2(6):341. PMID: 12882324 pdf
The DNA sequence of human chromosome 7. LaDeana W. Hillier, Robert S. Fulton, Lucinda A. Fulton, Tina A. Graves, Kymberlie H. Pepin, Caryn Wagner-McPherson, Dan Layman, Jason Maas, Sara Jaeger, Rebecca Walker, Kristine Wylie, Mandeep Sekhon, Michael C. Becker, Michelle D. O'Laughlin, Mark E. Schaller, Ginger A. Fewell, Kimberly D. Delehaunty, Tracie L. Miner, William E. Nash, Matt Cordes, Hui Du, Hui Sun, Jennifer Edwards, Holland Bradshaw-Cordum, Johar Ali, Stephanie Andrews, Amber Isak, Andrew VanBrunt, Christine Nguyen, Feiyu Du, Betty Lamar, Laura Courtney, Joelle Kalicki, Philip Ozersky, Lauren Bielicki, Kelsi Scott, Andrea Holmes, Richard Harkins, Anthony Harris, Cynthia Madsen Strong, Shunfang Hou, Chad Tomlinson, Sara Dauphin-Kohlberg, Amy Kozlowicz-Reilly, Shawn Leonard, Theresa Rohlfing, Susan M. Rock, Aye-Mon Tin-Wollam, Amanda Abbott, Patrick Minx, Rachel Maupin, Catrina Strowmatt, Phil Latreille, Nancy Miller, Doug Johnson, Jennifer Murray, Jeffrey P. Woessner, Michael C. Wendl, Shiaw-Pyng Yang, Brian R. Schultz, John W. Wallis, John Spieth, Tamberlyn A. Bieri, Joanne O. Nelson, Nicolas Berkowicz, Patricia E. Wohldmann, Lisa L. Cook, Matthew T. Hickenbotham, James Eldred, Donald Williams, Joseph A. Bedell, Elaine R. Mardis, Sandra W. Clifton, Stephanie L. Chissoe, Marco A. Marra,, Christopher Raymond, Eric Haugen, Will Gillett, Yang Zhou, Rose James, Karen Phelps, Shawn Iadanoto, Kerry Bubb, Elizabeth Simms, Ruth Levy, James Clendenning, Rajinder Kaul, W. James Kent, Terrence S. Furey, Robert A. Baertsch, Michael R. Brent, Evan Keibler, Paul Flicek, Peer Bork, Mikita Suyama, Jeffrey A. Bailey, Matthew E. Portnoy, David Torrents, Asif T. Chinwalla, Warren R. Gish, Sean R. Eddy, John D. McPherson,, Maynard V. Olson, Evan E. Eichler, Eric D. Green, Robert H. Waterston, and Richard K. Wilson. Nature. 2003 Jul 10;424(6945):157-64. PMID: 12853948 pdf